VISDB Viral Integration Site DataBase

VIS ID

TVIS44020153

Fusion event

HTLV-1-OSTF1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr9

Cytoband

q21.13

Reference genome

Start

End

77720848/75105932 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-429 ; hsa-mir-1-3p ; hsa-mir-26b-5p ; hsa-mir-4735-5p ; hsa-mir-4668-3p ; hsa-mir-548c-3p ; hsa-mir-6844 ; hsa-mir-378a-5p ; hsa-mir-6821-3p ; hsa-mir-6749-3p ; hsa-mir-6790-3p ; hsa-mir-3653-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-7108-3p ; hsa-mir-4258 ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-6131 ; hsa-mir-4755-3p ; hsa-mir-3663-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-1273f ; hsa-mir-1289 ; hsa-mir-129-5p ; hsa-mir-136-5p ; hsa-mir-143-3p ; hsa-mir-3120-5p ; hsa-mir-3198 ; hsa-mir-325 ; hsa-mir-3685 ; hsa-mir-384 ; hsa-mir-411-5p ; hsa-mir-4294 ; hsa-mir-4309 ; hsa-mir-4317 ; hsa-mir-4534 ; hsa-mir-4708-5p ; hsa-mir-4770 ; hsa-mir-5571-3p ; hsa-mir-6088 ; hsa-mir-6514-5p ; hsa-mir-6832-5p ; hsa-mir-6888-3p ; hsa-mir-7975 ; hsa-mir-8055 ; hsa-mir-8082

Nearest miRNA

hsa-mir-101-2/Upstream/4295848; hsa-let-7a-1/Downstream/8863816;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/17029, chr9-CpG: 148/Downstream/784382

Upstream sequence

GATTTTTATGTTATATGATGGAGACTAAATAAAATTAACTAGTAGGTATGGCCCATCAAGATGTAAAAGTAAACCAAGTTTGCTGAAAGGCACTGAAAAG

Downstream sequence

TATAAGCAAAGAAAAAATGGATTAGAAAGGCACACTGTTAATAAACAGAACGCTCTTGTCAGAAAACACTCAGGCTACTGTTTTTAAAGAGTCCGCTATT