Basic Information
VIS ID
TVIS44020162
Fusion event
HTLV-1-LOC105376107 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
84699273/82084358 (Hg38)
End
84699273/82084358 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105376107
Nearest miRNA
hsa-mir-101-2/Upstream/11274274; hsa-let-7a-1/Downstream/1885390;
Nearest TSS
ENST00000422679/Upstream/95570; ENST00000436084/Downstream/320830;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/394272, chr9-CpG: 137/Downstream/977742
Nearby gene
SPATA31D1(No orient, 89102)
Upstream sequence
CTTGAGAGTGCAATTTCTCAGCCTCTGTTGAAAAGGATTTGGGCTTCACTTTTGCAAAGCCAAAAGGCTAGAAGTTCAATGGAAAtgtttttgtttttga
Downstream sequence
ttttgttttGGCCAAATCTATAAATAGTGTTTTTATTGTTTTGTGGAATAACAGGATCAACAAGTTATGACATTATTATAGTATTTTGTCCCTGCTACAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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