VISDB Viral Integration Site DataBase

VIS ID

TVIS44020178

Fusion event

HTLV-1-AOPEP integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr9

Cytoband

q22.32

Reference genome

Start

End

97718482/94956200 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-218-5p ; hsa-mir-6820-5p ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-6087 ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-214-3p ; hsa-mir-6510-5p ; hsa-mir-6089 ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-518f-3p ; hsa-mir-518c-3p ; hsa-mir-518d-3p ; hsa-mir-518b ; hsa-mir-518a-3p ; hsa-mir-6849-3p ; hsa-mir-4293 ; hsa-mir-6771-3p ; hsa-mir-3180-5p ; hsa-mir-2355-5p ; hsa-mir-1236-3p ; hsa-mir-6893-3p ; hsa-mir-370-3p ; hsa-mir-4793-5p ; hsa-mir-510-5p ; hsa-mir-4786-5p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-640 ; hsa-mir-378a-5p ; hsa-mir-1193 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-1224-3p ; hsa-mir-2392 ; hsa-mir-1306-5p ; hsa-mir-1343-3p ; hsa-mir-23a-5p ; hsa-mir-23b-5p ; hsa-mir-4264 ; hsa-mir-4279 ; hsa-mir-4722-3p ; hsa-mir-4740-3p ; hsa-mir-498 ; hsa-mir-622 ; hsa-mir-660-3p ; hsa-mir-6727-3p ; hsa-mir-6742-3p ; hsa-mir-6747-3p ; hsa-mir-6783-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p

Nearest miRNA

hsa-let-7a-1/Upstream/146143; hsa-mir-12126/Downstream/109150;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/229310, chr9-CpG: 164/Downstream/48167

Upstream sequence

TAGGGAAAAGGTTTCCCATTTAATGCAGTGGGAAAAATAGGAAGTTAATGAAATGGACACAAAGAAAGGGTTGCTTCAGGGAAGGTGATCTCTCTGTAGT

Downstream sequence

TTTGAAATAAACTATAACCCAAAGCTGTCTCGTACACAGTGATAGTTAAAGACAAAAATAAAACAATcctgccgttctctttacctggacttatctttgg