Basic Information
VIS ID
TVIS44020185
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q24.31
Reference genome
GRCh37/hg19
Start
101864173/100104416 (Hg38)
End
101864173/100104416 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Nearest miRNA
hsa-mir-107/Upstream/1179848; hsa-mir-1307/Downstream/870569;
Nearest TSS
ENST00000439456/Upstream/22539; ENST00000443919/Downstream/81613;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/38987, chr10-CpG: 43/Downstream/10648
Nearby gene
CPN1(-22531) ;
Upstream sequence
gggagggatccagtgggaggtaattgaatcatgagggcgagtttttcctgtgctgttctcgtgataatggataagtctcgtggcatctgacggttttcta
Downstream sequence
aaggggagtttgcctgcacacgttctcttgtctgctgccatgtaagacatgcttttgcttctccttttccttctaccatgattgtgaggcctccccaggc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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