Basic Information
VIS ID
TVIS44020198
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
110304126/108544368 (Hg38)
End
110304126/108544368 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Nearest miRNA
hsa-mir-107/Upstream/4275963; hsa-mir-202/Downstream/2353722;
Nearest TSS
ENST00000439456/Upstream/346519; ENST00000421481/Downstream/17447;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/77661, chr10-CpG: 43/Downstream/367598
Nearby gene
LINC01435(No orient, 475075)
Upstream sequence
gacaggggtcccttccctatttggtagccaaggtggagagaggggacagcttacatcattatttcttttatgtatttctcggaaagatcaaatactttaa
Downstream sequence
tactttcactaattctgctactactatctagaaggcagagccaggtgtacagggcagaacatgaaagtggaccaggagcgtgaccgctgaagcacagcat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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