Basic Information
VIS ID
TVIS44020232
Fusion event
HTLV-1-LOC107984162 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p13
Reference genome
GRCh37/hg19
Start
15212190/15170191 (Hg38)
End
15212190/15170191 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107984162
Nearest miRNA
hsa-mir-1265/Upstream/733530; hsa-mir-107/Downstream/2674916;
Nearest TSS
ENST00000439456/Upstream/1498; ENST00000433455/Downstream/67301;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/1476, chr10-CpG: 22/Downstream/42408
Nearby gene
NMT2(-1481) ;
Upstream sequence
CTAAAATTCTGTAAGAAGGGCAAATGGGGTCAAAACACAAAAGGAAATACAATATTGCCTTTAACAACGGCAACTATTTCTGAGGCAAAATGTCACATGT
Downstream sequence
CACCTCTGTGAAACTTTAGGATAGAAGCAAATACAGATGAGTGAGGTTCCTGCAGCTCATCTCTGTGAACATGGATTGTTGGAGAACCCGCAGCCCGCTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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