Basic Information
VIS ID
TVIS44020236
Fusion event
HTLV-1-ST8SIA6-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p12.33
Reference genome
GRCh37/hg19
Start
17434265/17392266 (Hg38)
End
17434265/17392266 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
ST8SIA6-AS1
Nearest miRNA
hsa-mir-1265/Upstream/2955605; hsa-mir-107/Downstream/452841;
Nearest TSS
ENST00000439456/Upstream/5272; ENST00000451190/Downstream/15761;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/161648, chr10-CpG: 103/Downstream/61142
Upstream sequence
tatcaatcaacaaataaccaaacaaatgaatatagaattatgaaccgtgattggttatggttgaaccagagtaggtggctcagaagagtaggtctctact
Downstream sequence
cacactgaggggtcagaggaggcctccaagtgagtgtcatttagatggagacacccaaggatgatccaaacaaagtgggtagtgcgttcaaggcagagga
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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