VISDB Viral Integration Site DataBase

VIS ID

TVIS44020248

Fusion event

HTLV-1-MSRB2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr10

Cytoband

p12.2

Reference genome

Start

End

23407293/23118364 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-561-5p ; hsa-mir-383-3p ; hsa-mir-3922-5p ; hsa-mir-6878-3p ; hsa-mir-6811-5p ; hsa-mir-6511b-5p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-657 ; hsa-mir-3665 ; hsa-mir-3934-5p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-150-5p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-4279 ; hsa-mir-4722-3p ; hsa-mir-498 ; hsa-mir-5571-5p ; hsa-mir-562 ; hsa-mir-5697 ; hsa-mir-6727-3p ; hsa-mir-6747-3p ; hsa-mir-6778-3p ; hsa-mir-6814-5p

Nearest miRNA

hsa-mir-1265/Upstream/1621723; hsa-mir-107/Downstream/1157321;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/22215, chr10-CpG: 30/Downstream/54007

Upstream sequence

CTAGGCTTCCTTCTGTGTTCATAGTCTAGGGATTTGATTCTTTGCTACTTTTTCTTCTTAGATTAGttttttgtttttttttttttttttttGGCTGGGT

Downstream sequence

CTAACATTCAGTTCTTCTCTTTCTTCCTTAGATAGAGAGAGCCATTTCCTTGCCACAGCAATTTTTGAAGTCTATTTTCCCAGTGCCATTTAAGGGAGCT