Basic Information
VIS ID
TVIS44020251
Fusion event
HTLV-1-SELENOOLP integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
26962764/26673835 (Hg38)
End
26962764/26673835 (Hg38)
Orient
+
Location type
Intronic
Target gene
SELENOOLP
Nearest miRNA
hsa-mir-1265/Upstream/2398054; hsa-mir-107/Downstream/1615423;
Nearest TSS
ENST00000439456/Upstream/30607; ENST00000458171/Downstream/23824;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/106482, chr10-CpG: 105/Downstream/23378
Upstream sequence
TTCTCTAAAATCACAGAAGCAAAGCTGCAGCCATGAACCCACTTCATTTCTTTCATTTTGCCATTTCATCCAATCTATCCTAACCAAGTAAATCCAAATA
Downstream sequence
CTAAGGACTGCCACCACATGGCATTTAAAAATATTTTAGACTTCTTTCTCTCAGCTGCTGGGACTATTCACATTCTGAGCTGGCCTGGAAGTTCTGTATG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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