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TVIS44020255
Basic Information
VIS ID
TVIS44020255
Fusion event
HTLV-1-ARHGAP12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
32165084/31876156 (Hg38)
End
32165084/31876156 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARHGAP12
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-340-5p
;
hsa-mir-130b-3p
;
hsa-mir-142-3p
;
hsa-mir-128-3p
;
hsa-mir-181a-5p
;
hsa-mir-93-5p
;
hsa-mir-20a-5p
;
hsa-mir-19b-3p
;
hsa-mir-125a-5p
;
hsa-mir-199a-5p
;
hsa-mir-106b-5p
;
hsa-mir-6813-3p
;
hsa-mir-3200-3p
;
hsa-mir-8485
;
hsa-mir-548aw
;
hsa-mir-3192-3p
;
hsa-mir-1468-3p
;
hsa-mir-548x-5p
;
hsa-mir-548g-5p
;
hsa-mir-548f-5p
;
hsa-mir-548aj-5p
;
hsa-mir-3151-3p
;
hsa-mir-616-5p
;
hsa-mir-373-5p
;
hsa-mir-371b-5p
;
hsa-mir-8063
;
hsa-mir-3613-3p
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-551b-5p
;
hsa-mir-548t-5p
;
hsa-mir-548az-5p
;
hsa-mir-519d-3p
;
hsa-mir-106a-5p
;
hsa-mir-17-5p
;
hsa-mir-526b-3p
;
hsa-mir-20b-5p
;
hsa-mir-301a-3p
;
hsa-mir-301b-3p
;
hsa-mir-130a-3p
;
hsa-mir-3666
;
hsa-mir-4295
;
hsa-mir-454-3p
;
hsa-mir-19a-3p
;
hsa-mir-4721
;
hsa-mir-1226-5p
;
hsa-mir-3616-3p
;
hsa-mir-545-3p
;
hsa-mir-3065-5p
;
hsa-mir-330-3p
;
hsa-mir-6838-5p
;
hsa-mir-4512
;
hsa-mir-497-5p
;
hsa-mir-424-5p
;
hsa-mir-195-5p
;
hsa-mir-16-5p
;
hsa-mir-15b-5p
;
hsa-mir-4517
;
hsa-mir-15a-5p
;
hsa-mir-4762-3p
;
hsa-mir-6890-3p
;
hsa-mir-510-3p
;
hsa-mir-377-3p
;
hsa-mir-494-3p
;
hsa-mir-3658
;
hsa-mir-499a-5p
;
hsa-mir-208b-3p
;
hsa-mir-208a-3p
;
hsa-mir-8087
;
hsa-mir-4432
Nearest miRNA
hsa-mir-1265/Upstream/1507491; hsa-mir-107/Downstream/3203442;
Nearest TSS
ENST00000439456/Upstream/21976;
ENST00000628416/Downstream/32718;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/115661
,
chr10-CpG: 16/Downstream/51817
Upstream sequence
agttgcttccaccttttggctatagtgaacaattctgctatgaacatggtgtacaaacacctttttgaatccctggcttacagttctttggggtaggtac
Downstream sequence
ccagaGCCCTTCTCTTTTGAAACTCCTCAAATAAAACTTACCTATTGCTCTAAAGGTCATCATAAAAAAAATAACATCAggccgggcacagtggctcacg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Sample Information
×
Sample name
HAM/TSP#2
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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