VISDB Viral Integration Site DataBase

VIS ID

TVIS44020256

Fusion event

HTLV-1-KIF5B integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr10

Cytoband

p11.22

Reference genome

Start

End

32306009/32017081 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-128-3p ; hsa-mir-1-3p ; hsa-mir-215-5p ; hsa-mir-34a-5p ; hsa-mir-192-5p ; hsa-mir-103a-3p ; hsa-mir-30a-5p ; hsa-mir-16-5p ; hsa-mir-186-5p ; hsa-mir-2054 ; hsa-mir-32-3p ; hsa-mir-3190-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-203a-3p ; hsa-mir-6124 ; hsa-mir-142-3p ; hsa-mir-2053 ; hsa-mir-6073 ; hsa-mir-6862-5p ; hsa-mir-4253 ; hsa-mir-3945 ; hsa-mir-7852-3p ; hsa-mir-4255 ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-7161-5p ; hsa-mir-548u ; hsa-mir-4282 ; hsa-mir-1296-5p ; hsa-mir-4512 ; hsa-mir-7160-3p ; hsa-mir-6895-5p ; hsa-mir-892a ; hsa-mir-3121-3p ; hsa-mir-450a-1-3p ; hsa-mir-7703 ; hsa-mir-3147 ; hsa-mir-5196-5p ; hsa-mir-4425 ; hsa-mir-4747-5p ; hsa-mir-6828-5p ; hsa-mir-922 ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-5684 ; hsa-mir-4325 ; hsa-mir-92a-3p ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-92b-3p ; hsa-mir-25-3p ; hsa-mir-633 ; hsa-mir-7-5p ; hsa-mir-4496 ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-548g-3p ; hsa-mir-548av-3p ; hsa-mir-5197-3p ; hsa-mir-548s ; hsa-mir-655-3p ; hsa-mir-374c-5p ; hsa-mir-3926 ; hsa-mir-520f-5p ; hsa-mir-6849-3p ; hsa-mir-3675-3p ; hsa-mir-6771-3p ; hsa-mir-1228-3p ; hsa-mir-1273a ; hsa-mir-1273g-3p ; hsa-mir-4432 ; hsa-mir-4486 ; hsa-mir-451b ; hsa-mir-4649-5p ; hsa-mir-4696 ; hsa-mir-4793-3p ; hsa-mir-508-5p ; hsa-mir-6501-3p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6729-5p ; hsa-mir-766-3p ; hsa-mir-939-3p

Nearest miRNA

hsa-mir-1265/Upstream/1648416; hsa-mir-107/Downstream/3062517;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/87617, chr10-CpG: 101/Downstream/38541

Upstream sequence

TGCTAATGTGATTATTCCTCTTTCCCAACAGTGCCACTCTGCTAAGTTAGAAAATAGAGACAGATGCACCATGACAACACATAAAATTCGGATTACGTTT

Downstream sequence

TCCACTAAATGAAAGCATTCAAATTGAGCAAGGTTTAAAGGTTTTAATGTGTTCTACTAACCAATCTGTGCAGAATGCCCTCTTCTGGCCATATTCTTTG