Basic Information
VIS ID
TVIS44020258
Fusion event
HTLV-1-CCDC7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
32749773/32460845 (Hg38)
End
32749773/32460845 (Hg38)
Orient
-
Location type
Intronic
Target gene
CCDC7
Nearest miRNA
hsa-mir-1265/Upstream/2092180; hsa-mir-107/Downstream/2618753;
Nearest TSS
ENST00000439456/Upstream/9202; ENST00000638889/Downstream/20866;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/113118, chr10-CpG: 166/Downstream/496498
Upstream sequence
CTTagtgattctcagactttagcatgcaaagcaatcacctgcaggtctagttacaacacaaattgttagtcccacttctagaatttctgatttagtaggg
Downstream sequence
tagcgtggggcctgagaattttcagtactaataagtatgcttgtaggtggtgctgatgctgttgctgtggctccttactttttgaaccacAGATCTAGAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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