Basic Information
VIS ID
TVIS44020261
Fusion event
HTLV-1-CCDC7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
32833362/32544434 (Hg38)
End
32833362/32544434 (Hg38)
Orient
-
Location type
Intronic
Target gene
CCDC7
Nearest miRNA
hsa-mir-1265/Upstream/2175769; hsa-mir-107/Downstream/2535164;
Nearest TSS
ENST00000439456/Upstream/1108; ENST00000639290/Downstream/23289;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/196707, chr10-CpG: 166/Downstream/412909
Upstream sequence
TGATTAATACTTGCTCTGATAGTCATATATAGAGAAACATTATTACGTATGTGATTATAGGGTATATAtgtctgtgtgtgtgtatgtgtctctgtgtgtg
Downstream sequence
tgtgtACTAAAATTCTTCCTGAGATAATGTCTTTCTTGTTGATGGACTCTTCTCATCAAAGTTCAGAGAATGAAATGTCAAACCCAGGCATATTTATGTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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