VISDB Viral Integration Site DataBase

VIS ID

TVIS44020274

Fusion event

HTLV-1-ZNF487 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr10

Cytoband

q11.21

Reference genome

Start

End

43942981/43447533 (Hg38)

Orient

-

Location type

ncRNA_intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-629-3p ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-296-3p ; hsa-mir-4262 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-2355-3p ; hsa-mir-4646-3p ; hsa-mir-4433b-5p ; hsa-mir-376b-3p ; hsa-mir-376a-3p ; hsa-mir-4449 ; hsa-mir-664a-3p ; hsa-mir-329-5p ; hsa-mir-4748 ; hsa-mir-4464 ; hsa-mir-6818-5p ; hsa-mir-4452 ; hsa-mir-3191-5p ; hsa-mir-1257 ; hsa-mir-4653-5p ; hsa-mir-3921 ; hsa-mir-146a-3p ; hsa-mir-331-3p ; hsa-mir-6801-3p ; hsa-mir-6810-3p ; hsa-mir-5571-5p ; hsa-mir-498 ; hsa-mir-4279 ; hsa-mir-4284 ; hsa-mir-4772-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-1304-3p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-4277 ; hsa-mir-6890-3p ; hsa-mir-1306-5p ; hsa-mir-3613-3p ; hsa-mir-3672 ; hsa-mir-371a-5p ; hsa-mir-371b-5p ; hsa-mir-372-5p ; hsa-mir-373-5p ; hsa-mir-4797-5p ; hsa-mir-5586-3p ; hsa-mir-5692a ; hsa-mir-616-5p ; hsa-mir-6864-3p ; hsa-mir-759 ; hsa-mir-873-3p

Nearest miRNA

hsa-mir-1265/Upstream/449852; hsa-mir-107/Downstream/1716481;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/10309, chr10-CpG: 69/Downstream/7903

Upstream sequence

gtttcactatgttggccaggctggtcttgaactcctgacctcaagtgatctgcctgcctcgggctcccaaagtgctgggattacaggcgtgagccaccac

Downstream sequence

gcacagcctgaattatgacatttctaatctgcctggtgtaggaacaggcactattccatgccctgtgtgagcactgggcactattccctctgatcttttt