Basic Information
VIS ID
TVIS44020287
Fusion event
HTLV-1-LOC105378305 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
54447586/52687826 (Hg38)
End
54447586/52687826 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10G
Target gene
LOC105378305
Nearest miRNA
hsa-mir-1265/Upstream/1388171; hsa-mir-107/Downstream/1920048;
Nearest TSS
ENST00000439456/Upstream/126721; ENST00000422842/Downstream/67583;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/276608, chr10-CpG: 18/Downstream/183625
Nearby gene
MBL2(-77554) ;
Upstream sequence
GTAAAACAAATGGAGTGACATATGTGATGACCCTTGTTTTCAGAAAATATGTATATTTGTACCCCTAAATTATCCAGGGAACAAATAGAAAGTCTTAATC
Downstream sequence
AAATTAAATAAAGTCATTACCTGAAAGATAAATCTAAAAACCTCAATAACTTAACATTTGCTTTTAACTATTTAGAAAGTATTAGAAATATGTGCAATTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate