VISDB Viral Integration Site DataBase

VIS ID

TVIS44020303

Fusion event

HTLV-1-CCDC6 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr10

Cytoband

q21.2

Reference genome

Start

End

61578446/59818688 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-128-3p ; hsa-mir-181a-5p ; hsa-mir-331-5p ; hsa-mir-342-3p ; hsa-mir-99a-5p ; hsa-mir-92a-3p ; hsa-mir-548c-3p ; hsa-mir-671-5p ; hsa-mir-3190-3p ; hsa-mir-6079 ; hsa-mir-142-3p ; hsa-mir-146a-5p ; hsa-mir-146b-5p ; hsa-mir-580-5p ; hsa-mir-5572 ; hsa-mir-4260 ; hsa-mir-450a-2-3p ; hsa-mir-7156-5p ; hsa-mir-4273 ; hsa-mir-6803-5p ; hsa-mir-6751-5p ; hsa-mir-7109-5p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-2117 ; hsa-mir-6740-5p ; hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-7110-5p ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-6835-5p ; hsa-mir-6828-5p ; hsa-mir-6077 ; hsa-mir-873-5p ; hsa-mir-7854-3p ; hsa-mir-4264 ; hsa-mir-4797-3p ; hsa-mir-4328 ; hsa-mir-6165 ; hsa-mir-2113 ; hsa-mir-630 ; hsa-mir-5093 ; hsa-mir-4790-3p ; hsa-mir-506-5p ; hsa-mir-892c-5p ; hsa-mir-3688-3p ; hsa-mir-1252-3p ; hsa-mir-3646 ; hsa-mir-5692a ; hsa-mir-218-5p ; hsa-mir-576-3p ; hsa-mir-6833-5p ; hsa-mir-6864-5p ; hsa-mir-6126 ; hsa-mir-3148 ; hsa-mir-6124 ; hsa-mir-1252-5p ; hsa-mir-299-3p ; hsa-mir-4657 ; hsa-mir-4491 ; hsa-mir-512-3p ; hsa-mir-708-5p ; hsa-mir-3139 ; hsa-mir-28-5p ; hsa-mir-28-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-708-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-335-3p ; hsa-mir-4652-3p ; hsa-mir-1298-5p ; hsa-mir-4778-5p ; hsa-mir-8087 ; hsa-mir-130b-3p

Nearest miRNA

hsa-mir-1265/Upstream/2514129; hsa-mir-107/Downstream/3554269;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/108447, chr10-CpG: 22/Downstream/63381

Nearest cancer related gene

CCDC6(OG, No orient, 0)

Upstream sequence

agtttacttccatgtcccaaagatgtgcaatcggcatgtctacatagtccctctggagtgagtaagagtgtgtgtatgagtgtgtcctacaatgagttgg

Downstream sequence

tgccccatccaggattgggtcctgctttgtgccctgagctgccaggacaggctccagccacccttgatctgaactggaataagcacgttagaaaatgaat