Basic Information
VIS ID
TVIS44020323
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
72759770/71000013 (Hg38)
End
72759770/71000013 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1265/Upstream/3596603; hsa-mir-107/Downstream/790734;
Nearest TSS
ENST00000439456/Upstream/60880; ENST00000335350/Downstream/212557;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/81200, chr10-CpG: 161/Downstream/212305
Nearby gene
PCBD1(-111227) ;
Upstream sequence
CCTCTtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtAGAgggcagttaatgcccacaggcaacctttgaccaatgggagatgaaaactaatgaataaa
Downstream sequence
tacttccTGTGTTTATTGCCCTCGGGGCCtgtcttagttcaggctgctataacaaaataccttaggctaggtaatttacaagagaaagttatcgttcaca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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