Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene7221617071396934718159477174755971773498717451427175980971762917717770637180210571803882717971847179863471805601718066537178260171783600717605057176079771761264717614137180426471804373718015647180163371806552
Basic Information
VIS ID
TVIS44020324
Fusion event
HTLV-1-CDH23 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
73566309/71806552 (Hg38)
End
73566309/71806552 (Hg38)
Orient
-
Location type
Intronic
Target gene
CDH23
Nearest miRNA
hsa-mir-1265/Upstream/15752; hsa-mir-107/Downstream/914477;
Nearest TSS
ENST00000439456/Upstream/9696; ENST00000441348/Downstream/12719;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/32817, chr10-CpG: 41/Downstream/44352
Upstream sequence
atattgagctatattgagcgctgaaaaaaaaaaaggcagaccaaaatgcctgactcatggagctgataGCCCTGTCTTTGCCTGCACACACACATACACA
Downstream sequence
CACACAAAGCATGAAAATCAGCTCTGAttttttttttttttttttgagacagagtctcgctccgttgccgaggctggagtgcagtggcatgaccttgact
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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