Basic Information
VIS ID
TVIS44020336
Fusion event
HTLV-1-LIPK integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q23.31
Reference genome
GRCh37/hg19
Start
90495239/88735482 (Hg38)
End
90495239/88735482 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
LIPK
Nearest miRNA
hsa-mir-1265/Upstream/1231528; hsa-mir-107/Downstream/327853;
Nearest TSS
ENST00000439456/Upstream/10938; ENST00000404459/Downstream/25924;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/152018, chr10-CpG: 91/Downstream/144548
Upstream sequence
ttaaaagaagaacttgaggctcagagaacctaagcagcctgtcccgagtcacccagctaatggacggcagagcgagaatttgaacccagatctgaccagg
Downstream sequence
caacccatggtcAACAGTCTTTTTTATAGGTGGAAAAAAAAGTCTTTTTCCACTTTTTCAATGCCAACCTGAAGAAGTTAGtgaacaagggtgaccagct
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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