VISDB Viral Integration Site DataBase

VIS ID

TVIS44020372

Fusion event

HTLV-1-MICAL2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr11

Cytoband

p15.3

Reference genome

Start

End

12247510/12225963 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-6786-3p ; hsa-mir-4324 ; hsa-mir-4329 ; hsa-mir-5000-3p ; hsa-mir-4436a ; hsa-mir-4293 ; hsa-mir-4740-5p ; hsa-mir-7153-5p ; hsa-mir-146b-5p ; hsa-mir-146a-5p ; hsa-mir-589-5p ; hsa-mir-6857-3p ; hsa-mir-4251 ; hsa-mir-5188 ; hsa-mir-4773 ; hsa-mir-4730 ; hsa-mir-6850-5p ; hsa-mir-675-5p ; hsa-mir-4466 ; hsa-mir-4664-5p ; hsa-mir-342-5p ; hsa-mir-25-5p ; hsa-mir-5580-5p ; hsa-mir-3692-5p ; hsa-mir-5739 ; hsa-mir-185-5p ; hsa-mir-1908-5p ; hsa-mir-1911-3p ; hsa-mir-197-5p ; hsa-mir-3132 ; hsa-mir-3150b-3p ; hsa-mir-3170 ; hsa-mir-3529-5p ; hsa-mir-3614-5p ; hsa-mir-379-5p ; hsa-mir-4253 ; hsa-mir-4306 ; hsa-mir-4325 ; hsa-mir-4644 ; hsa-mir-4784 ; hsa-mir-5090 ; hsa-mir-5572 ; hsa-mir-6087 ; hsa-mir-6502-3p ; hsa-mir-663a ; hsa-mir-6731-5p ; hsa-mir-6737-5p ; hsa-mir-6758-5p ; hsa-mir-6760-5p ; hsa-mir-6775-5p ; hsa-mir-6787-5p ; hsa-mir-6812-5p ; hsa-mir-6819-5p ; hsa-mir-6855-5p ; hsa-mir-6856-5p ; hsa-mir-6862-5p ; hsa-mir-6881-5p ; hsa-mir-744-5p ; hsa-mir-8085

Nearest miRNA

hsa-mir-210/Upstream/62196; hsa-let-7a-2/Downstream/3743570;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/114494, chr11-CpG: 72/Downstream/151647

Upstream sequence

AAGTAAGGGATATATTTAAAAGTAAAATAGCTCATAAATGTTCCCAAGAGGTTTAAATCATTTTCTGATGGCTTTAGCCCAGGCAGCAATAACGTCATCA

Downstream sequence

TGGCCCAGGTCTGATTTTGTCCCTTCCTGACCAGTGGAGTGGTGGGTGAGAACTGGGAGTAGGGGCTGGGGTCACTATTCCTCCCCTGTAACCTGCCGAC