Basic Information
VIS ID
TVIS44020414
Fusion event
HTLV-1-MPPED2-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
30617419/30595872 (Hg38)
End
30617419/30595872 (Hg38)
Orient
-
Location type
Intronic
Target gene
MPPED2-AS1
Nearest miRNA
hsa-mir-210/Upstream/2118324; hsa-let-7a-2/Downstream/4345965;
Nearest TSS
ENST00000527297/Upstream/9000; ENST00000528872/Downstream/310833;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/9291, chr11-CpG: 37/Downstream/773668
Nearby gene
MPPED2(-9489) ;
Upstream sequence
CACAAGGGGTTTTCAAATCAAAGGTTGTTGGGACATTTGTGATTCTAAAAAGAACATTGATGATTTTTCTTGGCTTTTAGTAGTGATTTTATTCATAATG
Downstream sequence
TATAATAAAAAACAAGATATTGGGTATAATTCTCTGTATTATTTCTCTGTTTGAATGGACCTTTTCATTCAAGGTGTTATTTAATATAATTTTGTTCAGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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