Basic Information
VIS ID
TVIS44020434
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
45942830/45921279 (Hg38)
End
45942830/45921279 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-129-2/Upstream/229503; hsa-let-7a-2/Downstream/455123;
Nearest TSS
ENST00000527297/Upstream/2467; ENST00000525609/Downstream/342;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/2694, chr11-CpG: 127/Downstream/683
Nearby gene
LARGE2(+342) ;
Upstream sequence
CCACCCCAGCTTTAGGCTACAGATGAAGATCAGGGAGGCTGGAGGCTCAAGCTCCAGACGCCTGAGTGGCCAGTGCATGGCCCTTCTCAATTTCTGGGTG
Downstream sequence
CACAAGGAGCCACCATCAGTCTCCATAGCAACCATTATCCCTGCCCTCCAGAGACCCAAAGCCTGACCTTCCCCATCTCCCAGAGAAAGGGGGTCTCAGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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