Basic Information
VIS ID
TVIS44020446
Fusion event
HTLV-1-LOC105369325 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
60806801/61039329 (Hg38)
End
60806801/61039329 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105369325
Nearest miRNA
hsa-mir-129-2/Upstream/830173; hsa-let-7a-2/Downstream/469267;
Nearest TSS
ENST00000527297/Upstream/22426; ENST00000536495/Downstream/16408;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/30494, chr11-CpG: 76/Downstream/121759
Nearby gene
CD6(+18953) ;
Upstream sequence
ggaatttgttagagtgaattttcccaactctgtccaagttggaggccaaaaatgtcacaatgtaatctagagtcaaattattttttactttttaaaatga
Downstream sequence
tgttgaaggccaggtggggtggctcacgtatgtaatccaagcactttggaaggccgaggcaggtggattacttgaggtcaggagttcgagaccagcctgg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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