Basic Information
VIS ID
TVIS44020461
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.4
Reference genome
GRCh37/hg19
Start
74720091/75009046 (Hg38)
End
74720091/75009046 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA11H
Nearest miRNA
hsa-mir-10392/Upstream/288709; hsa-let-7a-2/Downstream/326046;
Nearest TSS
ENST00000527297/Upstream/20102; ENST00000531457/Downstream/80708;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/19905, chr11-CpG: 230/Downstream/231556
Nearby gene
NEU3(+1348) ;
Upstream sequence
ACTCATAAGAGGTCCATCTCTAAATTGCCCTCCTCTTACTTCTTCCCCCTGCCTCATGTTTTTTCTCTTTAATGACTAGCATCGAAACTCTTTAAATGGG
Downstream sequence
GCAGGCCTGTGTTCTTATCTCAGGAATAGTAAGAAAAGGGGGTTGGGAACAGGGGAAATCCAGAATAAAGACTTGAGAAAGGAACAGAGTGGGTGATGGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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