Basic Information
VIS ID
TVIS44020478
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
85894182/86183140 (Hg38)
End
85894182/86183140 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA11F
Nearest miRNA
hsa-mir-10392/Upstream/4292304; hsa-let-7a-2/Downstream/95193;
Nearest TSS
ENST00000527297/Upstream/113258; ENST00000533228/Downstream/10342;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/113785, chr11-CpG: 18/Downstream/61203
Nearby gene
EED(+61244) ;
Nearest cancer related gene
EED(TSG, +61244) ;
Upstream sequence
tgaatgccccagtgtgtgggtgtgtgggcatgcacggtgtggatagaagagaagaggaagggaagagaatgggggaaagcttcctagaggaggtcaacct
Downstream sequence
ggggcgggaacttgataggcaggagataaatgtggggaggaggaagtatacccaggcaaggagagcaccatgtgctgagtcacaaatacgtgaaggaatg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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