Basic Information
VIS ID
TVIS44020484
Fusion event
HTLV-1-LINC02748 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
90910098/91176930 (Hg38)
End
90910098/91176930 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC02748
Nearest miRNA
hsa-mir-10392/Upstream/307728; hsa-let-7a-2/Downstream/2556744;
Nearest TSS
ENST00000527297/Upstream/18847; ENST00000577699/Downstream/617432;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/953740, chr11-CpG: 204/Downstream/1047539
Nearby gene
DISC1FP1(No orient, 261878)
Upstream sequence
AACCCAAGTGAGAAACTTATTACCACAATCAATCACCATTCAATACAAAACCTAGTACAGAACTAATGTACAGCACTCACATTTGGAGTCATCTCAAAGA
Downstream sequence
TTAGAAACTTTCATTTCTTTTctaacctctagatggatgccgttggttagagtgatccataggccaataagctgtggccagtgaaccatagttatatgat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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