Basic Information
VIS ID
TVIS44020496
Fusion event
HTLV-1-BTBD11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
107768714/107374937 (Hg38)
End
107768714/107374937 (Hg38)
Orient
+
Location type
Intronic
Target gene
BTBD11
Nearest miRNA
hsa-let-7i/Upstream/2783221; hsa-mir-1178/Downstream/1260873;
Nearest TSS
ENST00000382841/Upstream/54349; ENST00000494235/Downstream/205713;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/54607, chr12-CpG: 46/Downstream/206128
Upstream sequence
TCAAAAAACCATTTAGGAGTAGCTTTCCTCTACAATGAATAATTTCATCTTTCCTCATGCTCTGGTACCCACACTCACCTGAGATCTTTGACTGTTTTCT
Downstream sequence
CTCTTGGGCCCTGAATGAATGCTTTGGGATGGAGGCAGTAGCTGGCTTTGGGGAAAGGTTAAGTCTTTTTGGCTTCCTCTGGTCATGCAACACACAGAGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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