Basic Information
VIS ID
TVIS44020525
Fusion event
HTLV-1-ADGRD1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.33
Reference genome
GRCh37/hg19
Start
131608749/131124204 (Hg38)
End
131608749/131124204 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
ADGRD1
Nearest miRNA
hsa-let-7i/Upstream/2830026; hsa-mir-6763/Downstream/1457793;
Nearest TSS
ENST00000382841/Upstream/2250; ENST00000536191/Downstream/40807;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/1750, chr12-CpG: 24/Downstream/14448
Upstream sequence
GGGGAGTGCCGTGGAGGGGAGTTGGGGGTCTTGTCCCTCTCACGTCTTCAGAGGATCCCAGGGTTTGTGCCATCTGGGCCAATTCCTCATTTACCCACAA
Downstream sequence
GTCATCAGCCTTATTTCCAGATGAAGAAAGCAGGTTTTGGGATAACAAGTATAGCATGACCCCATTTGTTTAAAAAGTTAAAAGCTCTATATGGGTACAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate