VISDB Viral Integration Site DataBase

VIS ID

TVIS44020528

Fusion event

HTLV-1-GRIN2B integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr12

Cytoband

p13.1

Reference genome

Start

End

14073342/13920408 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1277-5p ; hsa-mir-297 ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-511-3p ; hsa-mir-5011-5p ; hsa-mir-4768-5p ; hsa-mir-6833-3p ; hsa-mir-6807-5p ; hsa-mir-4303 ; hsa-mir-6873-3p ; hsa-mir-6751-3p ; hsa-mir-1199-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-4267 ; hsa-mir-6858-3p ; hsa-mir-1179 ; hsa-mir-4762-3p ; hsa-mir-4766-5p ; hsa-mir-3160-5p ; hsa-mir-500a-5p ; hsa-mir-495-5p ; hsa-mir-6749-3p ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-4769-3p ; hsa-mir-4469 ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-5196-3p ; hsa-mir-6502-3p ; hsa-mir-126-3p ; hsa-mir-3180-5p ; hsa-mir-6515-3p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-6795-3p ; hsa-mir-6887-3p ; hsa-mir-501-5p ; hsa-mir-670-3p ; hsa-mir-1304-3p ; hsa-mir-3691-3p ; hsa-mir-483-3p ; hsa-mir-3184-3p ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-6849-3p ; hsa-mir-3614-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-5699-5p ; hsa-mir-519d-5p ; hsa-mir-1265 ; hsa-mir-4257

Nearest miRNA

hsa-mir-1244-3/Upstream/1004490; hsa-let-7i/Downstream/3752891;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/356308, chr12-CpG: 23/Downstream/61284

Upstream sequence

CAACAGAATTAAATTTCCCCAACTCACTTACGCTTCTCACAGAAGCATCATTCATTGGTACTTTAACTTCTCAAGGAAAAAATTCAAAGGAATAGAATGG

Downstream sequence

AAGTAGGGAAAAGATGGGATAAGACTGCTTTATCCTAGGCAAAAACATCATTTTGTAACtgtgcaggatattgtttgttgatccttagcaccattctcac