Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene1866022718683169187380571868957218691853186758291867698218683549186840101868190718682056186970671869721618699142
Basic Information
VIS ID
TVIS44020539
Fusion event
HTLV-1-PLCZ1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
18852076/18699142 (Hg38)
End
18852076/18699142 (Hg38)
Orient
-
Location type
Intronic
Target gene
PLCZ1
Nearest miRNA
hsa-mir-1244-3/Upstream/1025748; hsa-let-7i/Downstream/5513279;
Nearest TSS
ENST00000382841/Upstream/4064; ENST00000536931/Downstream/2448;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/2787542, chr12-CpG: 131/Downstream/430249
Upstream sequence
CTCTTTCTCAGGCCCCGTTTTACCTTGGGCACTGCCAAACAGAATAACCACCTCAGTTTTAGAATTAGAGGCAGTGAAAGGAAGATGCAGAGACAGATGG
Downstream sequence
CACCTCTACAGGTGTGCAGTGGGGCATGCACACTCTGCACAGCCATCTGGTAGTCCAGCCTGGGCGCCATTTCTTCCCCTTCCTTCACCATAGGCATAGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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