Basic Information
VIS ID
TVIS44020573
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
49480372/49086589 (Hg38)
End
49480372/49086589 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA12A
Nearest miRNA
hsa-mir-1244-3/Upstream/314552; hsa-let-7i/Downstream/1147553;
Nearest TSS
ENST00000382841/Upstream/16564; ENST00000553174/Downstream/3619;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/16383, chr12-CpG: 80/Downstream/3229
Nearby gene
DHH(-2834) ;
Upstream sequence
CTGCAGATGTTCAGTAAATCCTGCTTGAAGAAAGGAAAGAAGGAATAAAAGACTGGATTCTGGGCAGATAAACAGGTCACTTGAAACTTTTCGGCAGTGG
Downstream sequence
TTCTCAACTCTGATTTCTCAATATGCAGAGAGGTATTGCCAGGGTGATCACAAAATGCTTCATAAATTCTCAAAACAAGATTACTTTTAATTATACTTCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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