Basic Information
VIS ID
TVIS44020583
Fusion event
HTLV-1-DNAJC14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
56221779/55827995 (Hg38)
End
56221779/55827995 (Hg38)
Orient
+
Location type
Exonic
Target gene
DNAJC14
miRNAs that regulate target gene
hsa-mir-378a-5p ; hsa-mir-320a
Nearest miRNA
hsa-mir-1244-3/Upstream/1490681; hsa-let-7i/Downstream/1366509;
Nearest TSS
ENST00000382841/Upstream/449; ENST00000550115/Downstream/1608;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/10226, chr12-CpG: 36/Downstream/2007
Upstream sequence
GCCACCAAAAGCCTGCCTGTCCAAGTTGACATAGTTCCTCGGCTCCCCACAATCCCAGGCCTTTGCGCTTATCTGCCTGACTTCGTTTCCGACCCAGCCG
Downstream sequence
ATGTCGACCAGGGGACCTGGGATCCCTACGTCCACCCTCCCGAGTATCCTCCTTCGTTGGAAAGCGGTGCCGCTGTCTCCGGGATGGGGGTTTCTTTCCG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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