Basic Information
VIS ID
TVIS44020588
Fusion event
HTLV-1-ARHGAP9 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
57880974/57487191 (Hg38)
End
57880974/57487191 (Hg38)
Orient
+
Location type
Intronic
Target gene
ARHGAP9
miRNAs that regulate target gene
hsa-mir-2681-5p ; hsa-mir-4724-3p
Nearest miRNA
hsa-mir-1228/Upstream/292615; hsa-let-7i/Downstream/25497;
Nearest TSS
ENST00000382841/Upstream/7325; ENST00000548146/Downstream/103;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/10792, chr12-CpG: 28/Downstream/776
Nearby gene
MARS(+762) ;
Upstream sequence
ctcagtctcccgggtagctgggattacaggcgcctgccaccatgcccagctaattttgtatttttagtagagacggggtttcagcatgttggccaggctg
Downstream sequence
gtctcgaactgctgacctcaggtgatccgcccgcctcgactccccaaagtgctggattacatgcataagccaccgcgcccggccTATGTACATTTTTGTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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