Basic Information
VIS ID
TVIS44020594
Fusion event
HTLV-1-C12orf56 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
64772682/64378902 (Hg38)
End
64772682/64378902 (Hg38)
Orient
-
Location type
Intronic
Target gene
C12orf56
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-let-7i/Upstream/555175; hsa-mir-1178/Downstream/243607;
Nearest TSS
ENST00000382841/Upstream/85519; ENST00000540203/Downstream/11624;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/156296, chr12-CpG: 73/Downstream/11328
Upstream sequence
cactttgggaggctgaggcaggtggatcacttgaggccaggagtttgagaccagtctggccaccatagtgaaatcccgtctcagttaaaaatacaaacat
Downstream sequence
tagccgggtgtggtggtgcgtgcctgtagtcccagctactcaggaggctgaggcaggagaatcacttgaacccaggaggcagaggttgcagtaagccaag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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