Basic Information
VIS ID
TVIS44020604
Fusion event
HTLV-1-LOC100507377 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
74630309/74236529 (Hg38)
End
74630309/74236529 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LOC100507377
Nearest miRNA
hsa-let-7i/Upstream/4651706; hsa-mir-1178/Downstream/5182728;
Nearest TSS
ENST00000382841/Upstream/197443; ENST00000519948/Downstream/47140;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/1962758, chr12-CpG: 38/Downstream/301183
Upstream sequence
ttctccaaaagacaggatttatggttctggaatcaagggatagaaatgggagtggcaccactcatcattatacctattcatccactagcaaaatgtttgc
Downstream sequence
ttcttgttcttgcaactttatgctcttctggcctagaggccttagttccagaggaagaaatgctttcactagaaggtacaataatgattttattaaactg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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