Basic Information
VIS ID
TVIS44020615
Fusion event
HTLV-1-LOC105369873 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
82672301/82278522 (Hg38)
End
82672301/82278522 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12B
Target gene
LOC105369873
Nearest miRNA
hsa-let-7i/Upstream/1120061; hsa-mir-1178/Downstream/4466546;
Nearest TSS
ENST00000382841/Upstream/324803; ENST00000547985/Downstream/77599;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/519627, chr12-CpG: 60/Downstream/79703
Nearby gene
CCDC59(-73782) ;
Upstream sequence
AGTCTTTATCACTTGGGAAAATAGTACTTTAAATACTAGTAATACTAGTAATGCTAGTAACTAAAAGCTAGATTTTAGTTGGGCAATTGCAGTACTTTtg
Downstream sequence
tcaatgcccttcagttaaagaccaccagaaacatacctgcagttgaacaagttgagtttattacttattacagtaaggaagaatacacataagaaactgt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate