Basic Information
VIS ID
TVIS44020616
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.31
Reference genome
GRCh37/hg19
Start
8411749/8259153 (Hg38)
End
8411749/8259153 (Hg38)
Orient
-
Location type
Intronic
Target gene
ENPP7P5 ; LOC112268090
Nearest miRNA
hsa-mir-141/Upstream/1294962; hsa-let-7i/Downstream/980314;
Nearest TSS
ENST00000382841/Upstream/23223; ENST00000535746/Downstream/62723;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/15036, chr12-CpG: 83/Downstream/130806
Nearby gene
FAM86FP(-16207) ;
Upstream sequence
agtcctgggattacaggcatgagccaccatacccagccACTCTTGATTAACTTAACGGAAATATTTACAGAGATTCTTTCTCTTCTGGGTTCTAGCGTCC
Downstream sequence
TATGTGTAACCTCTGCAGGTAATACATTTTCCTTCCTGATGATAGCATTTCTATGGTTGCTTTAACTCACAAATCTTCTAATACTTATTTATTCCATTTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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