Basic Information
VIS ID
TVIS44020618
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
84729877/84336098 (Hg38)
End
84729877/84336098 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA12B
Nearest miRNA
hsa-let-7i/Upstream/3177637; hsa-mir-1178/Downstream/2408970;
Nearest TSS
ENST00000382841/Upstream/51707; ENST00000393212/Downstream/531735;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/1648231, chr12-CpG: 17/Downstream/575323
Nearby gene
SLC6A15(-523390) ;
Upstream sequence
TATATTACAAACATTTTTACTTTTTTTGCTCACGTTTACCTTGAAAGTAAATTCAGTAGATCTAGGATCTCTGAAAAGCACACATTGCTTTATTAAAACT
Downstream sequence
TTTATTGCCGTTTCCTATTTATGGCACCATAAGAAATAACAGGGCCTAGAGACACGTTTTTAGGCTATAGTTTTCCAAGGTCATGAGATGTAAAATTTTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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