Basic Information
VIS ID
TVIS44020630
Fusion event
HTLV-1-LOC643339 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q22
Reference genome
GRCh37/hg19
Start
93653644/93259868 (Hg38)
End
93653644/93259868 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LOC643339
Nearest miRNA
hsa-let-7i/Upstream/6514719; hsa-mir-1178/Downstream/1301921;
Nearest TSS
ENST00000382841/Upstream/44189; ENST00000550056/Downstream/117840;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/330146, chr12-CpG: 85/Downstream/117821
Upstream sequence
gcctcctgggttcaagtgattctcctgcctttgcctcctgagtaactgggattacaggcacgcatcaccacactcagctaactttttgtatttttagtag
Downstream sequence
agacggggtttcactatgttggccaggctgtctcaaactcctgaccttgtgatctgcccgtcttggcctcgcaaaatgctgggattacaggtgtgagcca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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