Basic Information
VIS ID
TVIS44020676
Fusion event
HTLV-1-B3GLCT integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
31818920/31244783 (Hg38)
End
31818920/31244783 (Hg38)
Orient
+
Location type
Intronic
Target gene
B3GLCT
Nearest miRNA
hsa-mir-2276/Upstream/7082279; hsa-mir-1267/Downstream/8419251;
Nearest TSS
ENST00000623511/Upstream/44847; ENST00000461652/Downstream/15624;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/43886, chr13-CpG: 70/Downstream/601710
Upstream sequence
TGCTACTACATCTAAGTGTAATATTACATCTGTTTGGGTCTCTGTGTGCATTCatatatatatatgtgtatatatgtgtgtatatgtatatgACAAGAAT
Downstream sequence
AAAAGCTCTTGGGCATTTTTGGGGATTAGTAGATTAAAATTTATTTACAATTAAGATGACTTTGGCTTAATCAAGAGTTAATCAAGAGCAGGTTTCTGAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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