Basic Information
VIS ID
TVIS44020690
Fusion event
HTLV-1-LINC00571 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
38674605/38100468 (Hg38)
End
38674605/38100468 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC00571
Nearest miRNA
hsa-mir-2276/Upstream/13937964; hsa-mir-1267/Downstream/1563566;
Nearest TSS
ENST00000623511/Upstream/39015; ENST00000464423/Downstream/42764;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/230377, chr13-CpG: 32/Downstream/249352
Upstream sequence
TTCTGGTGACTTGCAAAAGGAAGAGCAAAACAAGTGAAAATCAAGCCAGATTCTAAAATTATGACAGTCTGTAAAGAAAATTAGTTATTAATTATGATGC
Downstream sequence
AGGTTTACAGCAATATTTGTTTTGAATTAAATATATTTTCATGAAAATGTAAACCAGGAATGACACAAAAATAAAAATCTTACCAATGGAAGAATTGTGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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