Basic Information
VIS ID
TVIS44020699
Fusion event
HTLV-1-ENOX1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.11
Reference genome
GRCh37/hg19
Start
44273275/43699139 (Hg38)
End
44273275/43699139 (Hg38)
Orient
+
Location type
Intronic
Target gene
ENOX1
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-599 ; hsa-mir-3161 ; hsa-mir-526b-5p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-5692a ; hsa-mir-2681-5p
Nearest miRNA
hsa-mir-2276/Upstream/2130744; hsa-mir-1267/Downstream/496990;
Nearest TSS
ENST00000623511/Upstream/155221; ENST00000604480/Downstream/87769;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/675419, chr13-CpG: 159/Downstream/86759
Upstream sequence
gcataatgactaattctggagcttgtgcagatactgggacaaacactgcaaaccttgtaaaggacaaaaaatcccagtgggtgataaatcagcatggttg
Downstream sequence
ctcaggccctccaagtagtatcatggaaaagtgcagtggcccctcatatcgcactgaggcatcagctaagaaatgacttgagggaagaatgcctcctatg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate