Basic Information
VIS ID
TVIS44020706
Fusion event
HTLV-1-PHF11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
50079609/49505473 (Hg38)
End
50079609/49505473 (Hg38)
Orient
-
Location type
Intronic
Target gene
PHF11
Nearest miRNA
hsa-mir-2276/Upstream/5309273; hsa-mir-1267/Downstream/490942;
Nearest TSS
ENST00000623511/Upstream/8360; ENST00000460489/Downstream/16456;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/8890, chr13-CpG: 80/Downstream/79777
Upstream sequence
CAGCCTTCTGACTTGGTGAAATGAAAGACCTAACTTAAAGAGACAGAGAAGAGATCTGGATAACAGAAGAGACTTAGGGATCACTTAAGCAGTTAACCTC
Downstream sequence
ATCTAAATTGAAAACTTTTCCCATTAAATGGTAAAATAAATCTTTCTTTCAAAACTAAAATTTGAAAATTATAAATAAAAGCTGTTTTCTACTACAGAAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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