Basic Information
VIS ID
TVIS44020707
Fusion event
HTLV-1-chr13 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
51167110/50592974 (Hg38)
End
51167110/50592974 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-15a/Upstream/543773; hsa-mir-1267/Downstream/755593;
Nearest TSS
ENST00000623511/Upstream/65525; ENST00000413510/Downstream/122509;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/459091, chr13-CpG: 62/Downstream/250261
Nearby gene
DLEU1(+64331) ;
Nearest cancer related gene
DLEU1(TSG, +64331) ;
Upstream sequence
agcaaactcatttggtggcaaaacgtgacttagactgatacaaggACTGATATATAAGGTTCAatgccccatatgagctttctaaatttcaaaacattct
Downstream sequence
gacatgcaaaccacatcaaaacccagggtttcaaataaaaaattgtggagctgAactgtaattcatttaactagacccttgttgactggcatttggattt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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