Basic Information
VIS ID
TVIS44020717
Fusion event
HTLV-1-LOC105370217 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
58062250/57488116 (Hg38)
End
58062250/57488116 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA13B
Target gene
LOC105370217
Nearest miRNA
hsa-mir-1297/Upstream/2313568; hsa-mir-1267/Downstream/3711682;
Nearest TSS
ENST00000623511/Upstream/320919; ENST00000615375/Downstream/143694;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/320667, chr13-CpG: 58/Downstream/141336
Nearby gene
PCDH17(+143539) ;
Upstream sequence
ACTAAAACTATGAAAAAATTAAAACTTACATATCCAAATGTTTAAAATACAATAGTTTGTTTATTCCATTACAGATTGTGACAATTACCCAGATTCTTAA
Downstream sequence
TACTTTTTTTTTTTTTCGGTCCTGCAGTTCTCAGCATACTTACTTGGAATTTAGCTGTGTGTTCCCTTAAGACTGCATGATGACTTTCACACGTTTAGGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate