Basic Information
VIS ID
TVIS44020738
Fusion event
HTLV-1-LOC105370251 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
68377876/67803744 (Hg38)
End
68377876/67803744 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA13B
Target gene
LOC105370251
Nearest miRNA
hsa-mir-1297/Upstream/1585420; hsa-mir-1267/Downstream/9894268;
Nearest TSS
ENST00000623511/Upstream/431357; ENST00000627910/Downstream/1074636;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/572417, chr13-CpG: 34/Downstream/1181028
Nearby gene
LINC00364(No orient, 423750)
Upstream sequence
GAGGCACCAGGTCTCCATTGAAATCATCTAACATCCCAGTTAGTAACTACTTAGCAAAGTTAGGAAGGCCTGGATTCCACAGACACAAAGGCTGGACAAA
Downstream sequence
TACCAGTTGGGTCTTAGTGGCAAAAGTTCTAGTCAACTGTGGGGTTGGCAACTAATAATATCTGCAATTCCACAGAGACTAAAACAAGTTAATATACTGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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