Basic Information
VIS ID
TVIS44020744
Fusion event
HTLV-1-chr13 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
71895219/71321087 (Hg38)
End
71895219/71321087 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA13B
Nearest miRNA
hsa-mir-1297/Upstream/5102763; hsa-mir-1267/Downstream/6376925;
Nearest TSS
ENST00000623511/Upstream/305946; ENST00000618209/Downstream/545682;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1213000, chr13-CpG: 62/Downstream/544143
Nearby gene
DACH1(-116879) ;
Nearest cancer related gene
DACH1(TSG, -116879) ;
Upstream sequence
ctgtgaacagcttttcccagaactctagatggccgacttctctgccattcagtgagccggggttgtaccctccctaacaagatcttgatctcagcctggg
Downstream sequence
gaacttctgcttgagtgttgtaacttagccctatgggtagtgactccttatacctattcctagaaattttacatttcactggacttcttcctcatcaact
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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