Basic Information
VIS ID
TVIS44020745
Fusion event
HTLV-1-LOC107984620 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
75562609/74988472 (Hg38)
End
75562609/74988472 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA13E
Target gene
LOC107984620
Nearest miRNA
hsa-mir-1297/Upstream/8770148; hsa-mir-1267/Downstream/2709540;
Nearest TSS
ENST00000623511/Upstream/431936; ENST00000434832/Downstream/262008;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/852791, chr13-CpG: 197/Downstream/492244
Nearby gene
CTAGE11P(-249280) ;
Upstream sequence
GAAATATAGGTGTATATGTAACCTGTAATGTATCCATCAGAACCCAAGGAAAGCTTTCATTAAGAAAAAGATTTGGGAGATAGTTAGTTACAATTGGACA
Downstream sequence
CACTTAAATTGTTTCTCTTAGAAATATGTATTCCTTGTTATTTTTTTTAATCTTCTTACTTTCAGTGTGTTTTACTCTCCTAAAAATCTAATTATCTAGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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