Basic Information
VIS ID
TVIS44020750
Fusion event
HTLV-1-chr13 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
77951500/77377365 (Hg38)
End
77951500/77377365 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA13E
Nearest miRNA
hsa-mir-1297/Upstream/11159041; hsa-mir-1267/Downstream/320647;
Nearest TSS
ENST00000623511/Upstream/50315; ENST00000471491/Downstream/158309;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/47628, chr13-CpG: 95/Downstream/320288
Nearby gene
MYCBP2(-50323) ;
Upstream sequence
TGTTAAGTGACTGCCACTCTTAAAGAACATCTTTGCTCTGCAACTTCCTTTTCCTGAATTATCTATAAAAATAGAAAAAACTGCAATTTACGCACCAGAC
Downstream sequence
TTTCTAAAAAATGTCTTAGAGGAGACACTTGACCTTGCCTAAACCCAAATCTTCAGTCCTTTTTAGGATCTACAACTTGTTATTTATCTTGCTCCTATTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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