Basic Information
VIS ID
TVIS44020795
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.33
Reference genome
GRCh37/hg19
Start
104754418/104288081 (Hg38)
End
104754418/104288081 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1185-1/Upstream/170567; hsa-mir-12121/Downstream/389613;
Nearest TSS
ENST00000550708/Upstream/64467; ENST00000331952/Downstream/90870;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/35996, chr14-CpG: 40/Downstream/46026
Nearby gene
KIF26A(+107183) ;
Upstream sequence
CTCACCACAAGGCCAATCACTAGCAAGATAAAAAAGGAGCACCCCGAAGGGCCGAGACCAGCTGTGCCTCCGGGCAGGGGAGGGGCTGCCCCTTCCTTAC
Downstream sequence
CTGAACTCAATTCATTTTATTTTTATTTTTTAACATAAAAGGCAATGGGAATTCAGTGAGTGGACAGCTAGCCACCTCTGTGGCTGCCTGCCGTGTGAGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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